Recombinant Human PITRM1, His-tagged

• Cat.No.: PITRM1-27541TH
• Product Overview: Recombinant fragment, corresponding to amino acids 364-1037 of Human PITRM1 with N terminal His tag; MWt 80 kDa.

Specification

• Description: Presequence protease, mitochondrial is an enzyme that in humans is encoded by the PITRM1 gene.
• Conjugation: HIS
• Source: E. coli
• Tissue specificity: Widely expressed. Expressed at higher level in muscle and heart compared to brain, pancreas, liver, lung and placenta.
• Form: Lyophilised:Reconstitute with 58 μl aqua dest.
• Storage buffer: Preservative: NoneConstituents: 0.5% Trehalose, 6M Urea, 100mM Sodium phosphate, 10mM Sodium chloride, pH 4.5
• Storage: Shipped at 4°C. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequences of amino acids: ALIESGLGTDFSPDVGYNGYTREAYFSVGLQGIAEKDIET VRSLIDRTIDEVVEKGFEDDRIEALLHKIEIQMKHQST SFGLMLTSYIASCWNHDGDPVELLKLGNQLAKFRQCLQ ENPKFLQEKVKQYFKNNQHKLTLSMRPDDKYHEKQAQVEA TKLKQKVEALSPGDRQQIYEKGLELRSQQSKPQDASCL PALKVSDIEPTIPVTELDVVLTAGDIPVQYCAQPTNGM VYFRAFSSLNTLPEELRPYVPLFCSVLTKLGCGLLDYREQAQQIELKTGGMSASPHVLPDDSHMDTYEQGVLFSSLCL DRNLPDMMQLWSEIFNNPCFEEEEHFKVLVKMTAQELA NGIPDSGHLYASIRAGRTLTPAGDLQETFSGMDQVRLM KRIAEMTDIKPILRKLPRIKKHLLNGDNMRCSVNATPQQM PQTEKAVEDFLRSIGRSKKERRPVRPHTVEKPVPSSSG GDAHVPHGSQVIRKLVMEPTFKPWQMKTHFLMPFPVNY VGECIRTVPYTDPDHASLKILARLMTAKFLHTEIREKGGAYGGGAKLSHNGIFTLYSYRDPNTIETLQSFGKAVDWAK SGKFTQQDIDEAKLSVFSTVDAPVAPSDKGMDHFLYGL SDEMKQAHREQLFAVSHDKLLAVSDRYLGTGKSTHGLA ILGPENPKIAKDPSWIIQ
• Sequence Similarities: Belongs to the peptidase M16 family. PreP subfamily.
• Protein length: 364-1037 a.a.

Gene Information

• Gene Name: PITRM1 pitrilysin metallopeptidase 1 [ Homo sapiens ]
• Official Symbol: PITRM1
• Synonyms: PITRM1; pitrilysin metallopeptidase 1; pitrilysin metalloproteinase 1; presequence protease, mitochondrial; hMP1; KIAA1104; MP1; PreP; PreP peptidasome
• Gene ID: 10531
• mRNA Refseq: NM_001242307
• Protein Refseq: NP_001229236
• Uniprot ID: Q5JRX3
• Chromosome Location: 10p15.2
• Function: enzyme activator activity; metal ion binding; metalloendopeptidase activity; peptidase activity; zinc ion binding