Recombinant Human PI4K2A

• Cat.No.: PI4K2A-30365TH
• Product Overview: Recombinant full length Human PI4K2A with a N terminal proprietary tag. Predicted molecular weight 79 kDa.

Specification

• Species: Human
• Source: Sf9 Cells
• Tag: Non
• Protein Length: 479 amino acids
• Description: Phosphatidylinositolpolyphosphates (PtdInsPs) are centrally involved in many biologic processes, ranging from cell growth and organization of the actin cytoskeleton to endo- and exocytosis. PI4KII phosphorylates PtdIns at the D-4 position, an essential step in the biosynthesis of PtdInsPs (Barylko et al.
• Molecular Weight: 79.000kDa inclusive of tags
• Biological activity: Specific activity is 95 nmol/min/mg
• Form: Liquid
• Purity: >95% by SDS-PAGE
• Storage buffer: Preservative: NoneConstituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 10mM Glutathione, 0.25mM DTT, 0.1mM EDTA, 0.1mM PMSF, pH 7.5
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.

Gene Information

• Gene Name: PI4K2A phosphatidylinositol 4-kinase type 2 alpha [ Homo sapiens ]
• Official Symbol: PI4K2A
• Synonyms: PI4K2A; phosphatidylinositol 4-kinase type 2 alpha; phosphatidylinositol 4-kinase type 2-alpha; DKFZP761G1923; PI4KII; PIK42A
• Gene ID: 55361
• mRNA Refseq: NM_018425
• Protein Refseq: NP_060895
• MIM: 609763
• Uniprot ID: Q9BTU6
• Chromosome Location: 10q24
• Pathway: 3-phosphoinositide biosynthesis, conserved biosystem; Canonical Wnt signaling pathway, organism-specific biosystem; D-myo-inositol (1,4,5)-trisphosphate biosynthesis, conserved biosystem; Inositol phosphate metabolism, organism-specific biosystem; Inositol phosphate metabolism, conserved biosystem
• Function: 1-phosphatidylinositol 4-kinase activity; ATP binding; kinase activity; magnesium ion binding; nucleotide binding