Recombinant Human PGM1 protein, MYC/DDK-tagged

• Cat.No.: PGM1-2920H
• Product Overview: Recombinant Human PGM1 fused with MYC/DDK tag at C-terminal was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: The protein encoded by this gene is an isozyme of phosphoglucomutase (PGM) and belongs to the phosphohexose mutase family. There are several PGM isozymes, which are encoded by different genes and catalyze the transfer of phosphate between the 1 and 6 positions of glucose. In most cell types, this PGM isozyme is predominant, representing about 90% of total PGM activity. In red cells, PGM2 is a major isozyme. This gene is highly polymorphic. Mutations in this gene cause glycogen storage disease type 14. Alternativley spliced transcript variants encoding different isoforms have been identified in this gene.
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 61.3 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: PGM1 phosphoglucomutase 1 [ Homo sapiens ]
• Official Symbol: PGM1
• Synonyms: PGM1; phosphoglucomutase 1; phosphoglucomutase-1; PGM 1; glucose phosphomutase 1; GSD14
• Gene ID: 5236
• mRNA Refseq: NM_002633
• Protein Refseq: NP_002624
• MIM: 171900
• UniProt ID: P36871
• Chromosome Location: 1p22.1
• Pathway: Amino sugar and nucleotide sugar metabolism, organism-specific biosystem; Amino sugar and nucleotide sugar metabolism, conserved biosystem; GDP-glucose biosynthesis, organism-specific biosystem; GDP-glucose biosynthesis, conserved biosystem; Galactose metabolism, organism-specific biosystem; Galactose metabolism, conserved biosystem; Glucose metabolism, organism-specific biosystem
• Function: isomerase activity; magnesium ion binding; phosphoglucomutase activity