Recombinant Human PGA4 Protein, Myc/DDK-tagged

• Cat.No.: PGA4-01H
• Product Overview: Recombinant protein of human pepsinogen 4, group I (pepsinogen A) (PGA4) with a C-Myc/DDK tag was expressed in HEK293T.

Specification

• Species: Human
• Source: HEK293
• Tag: Myc&DDK
• Description: This gene encodes a protein precursor of the digestive enzyme pepsin, a member of the peptidase A1 family of endopeptidases. The encoded precursor is secreted by gastric chief cells and undergoes autocatalytic cleavage in acidic conditions to form the active enzyme, which functions in the digestion of dietary proteins. This gene is found in a cluster of related genes on chromosome 11, each of which encodes one of multiple pepsinogens. Pepsinogen levels in serum may serve as a biomarker for atrophic gastritis and gastric cancer.
• Molecular Mass: 40.3 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: At -80 centigrade.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Gene Information

• Gene Name: PGA4 pepsinogen A4 [ Homo sapiens (human) ]
• Official Symbol: PGA4
• Synonyms: PGA4; pepsinogen A4; pepsin A-4; pepsinogen 4, group I (pepsinogen A); pepsinogen-4; pregnancy-associated glycoprotein; EC 3.4.23.1
• Gene ID: 643847
• mRNA Refseq: NM_001079808
• Protein Refseq: NP_001073276
• MIM: 169720
• UniProt ID: P0DJD7