Recombinant Human PFKFB2 Protein, His-tagged

• Cat.No.: PFKFB2-643H
• Product Overview: Recombinant Human PFKFB2, transcript variant 1, fused with His tag at N-terminal was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: The protein encoded by this gene is involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. The encoded protein has a 6-phosphofructo-2-kinase activity that catalyzes the synthesis of fructose-2,6-bisphosphate, and a fructose-2,6-biphosphatase activity that catalyzes the degradation of fructose-2,6-bisphosphate. This protein regulates fructose-2,6-bisphosphate levels in the heart, while a related enzyme encoded by a different gene regulates fructose-2,6-bisphosphate levels in the liver and muscle. This enzyme functions as a homodimer. Two transcript variants encoding two different isoforms have been found for this gene.
• Form: 25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1% Sarkosyl.
• Molecular Mass: 58.3 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 [ Homo sapiens ]
• Official Symbol: PFKFB2
• Synonyms: PFK-2/FBPase-2
• Gene ID: 5208
• mRNA Refseq: NM_006212.2
• Protein Refseq: NP_006203.2
• MIM: 171835
• UniProt ID: O60825