Recombinant Human PFDN4, His-tagged

• Cat.No.: PFDN4-26970TH
• Product Overview: Recombinant full length Human PFDN4 with an N terminal His tag ; mwt: 17.4 kDa

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 134 amino acids
• Description: This gene encodes a member of the prefoldin beta subunit family. The encoded protein is one of six subunits of prefoldin, a molecular chaperone complex that binds and stabilizes newly synthesized polypeptides, thereby allowing them to fold correctly. The complex, consisting of two alpha and four beta subunits, forms a double beta barrel assembly with six protruding coiled-coils.
• Conjugation: HIS
• Molecular Weight: 17.400kDa inclusive of tags
• Form: Liquid
• Purity: >90% by SDS-PAGE
• Storage buffer: Preservative: NoneConstituents: 10% Glycerol, 50mM Sodium chloride, 20mM Tris HCl, 1mM DTT, pH 7.5
• Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Sequences of amino acids: MGSSHHHHHH SSGLVPRGSH MAATMKKAAA EDVNVTFEDQ QKINKFARNT SRITELKEEI EVKKKQLQNL EDACDDIMLA DDDCLMIPYQ IGDVFISHSQ EETQEMLEEA KKNLQEEIDA LESRVESIQR VLADLKVQLY AKFGSNINLE ADES
• Sequence Similarities: Belongs to the prefoldin subunit beta family.

Gene Information

• Gene Name: PFDN4 prefoldin subunit 4 [ Homo sapiens ]
• Official Symbol: PFDN4
• Synonyms: PFDN4; prefoldin subunit 4; prefoldin 4; C 1; C1; PFD4
• Gene ID: 5203
• mRNA Refseq: NM_002623
• Protein Refseq: NP_002614
• MIM: 604898
• Uniprot ID: Q9NQP4
• Chromosome Location: 20q13.2
• Pathway: Chaperonin-mediated protein folding, organism-specific biosystem; Cooperation of Prefoldin and TriC/CCTin actin and tubulin folding, organism-specific biosystem; Metabolism of proteins, organism-specific biosystem; Prefoldin mediated transfer of substrateto CCT/TriC, organism-specific biosystem; Protein folding, organism-specific biosystem
• Function: chaperone binding; unfolded protein binding