Recombinant Human PFDN1, His-tagged

• Cat.No.: PFDN1-26969TH
• Product Overview: Recombinant fragment (amino acids 14 - 122) of Human PFDN1 with an N terminal His-tag.

Specification

• Description: This gene encodes a member of the prefoldin beta subunit family. The encoded protein is one of six subunits of prefoldin, a molecular chaperone complex that binds and stabilizes newly synthesized polypeptides, thereby allowing them to fold correctly. The complex, consisting of two alpha and four beta subunits, forms a double beta barrel assembly with six protruding coiled-coils.
• Protein length: 109 amino acids
• Conjugation: HIS
• Molecular Weight: 15.000kDa inclusive of tags
• Source: E. coli
• Form: Liquid
• Purity: >90% by SDS-PAGE
• Storage buffer: Preservative: 0% NoneConstituents: 20% Glycerol, 20mM Tris HCl, pH 8.0
• Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Sequences of amino acids: MGSSHHHHHH SSGLVPRGSH MTELQAKVID TQQKVKLADI QIEQLNRTKK HAHLTDTEIM TLVDETNMYE GVGRMFILQS KEAIHSQLLE KQKIAEEKIK ELEQKKSYLE RSVKEAEDNI REMLMARRAQ

Gene Information

• Gene Name: PFDN1 prefoldin subunit 1 [ Homo sapiens ]
• Official Symbol: PFDN1
• Synonyms: PFDN1; prefoldin subunit 1; prefoldin 1; PFD1
• Gene ID: 5201
• mRNA Refseq: NM_002622
• Protein Refseq: NP_002613
• MIM: 604897
• Uniprot ID: O60925
• Chromosome Location: 5q31
• Pathway: Chaperonin-mediated protein folding, organism-specific biosystem; Cooperation of Prefoldin and TriC/CCTin actin and tubulin folding, organism-specific biosystem; Metabolism of proteins, organism-specific biosystem; Prefoldin mediated transfer of substrateto CCT/TriC, organism-specific biosystem; Protein folding, organism-specific biosystem
• Function: sequence-specific DNA binding transcription factor activity; unfolded protein binding