Recombinant Human PEPD

• Cat.No.: PEPD-30836TH
• Product Overview: Recombinant Human PEPD was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: Non
• Protein Length: 2 to 493
• Description: This gene encodes a member of the peptidase family. The protein forms a homodimer that hydrolyzes dipeptides or tripeptides with C-terminal proline or hydroxyproline residues. The enzyme serves an important role in the recycling of proline, and may be rate limiting for the production of collagen. Mutations in this gene result in prolidase deficiency, which is characterized by the excretion of large amount of di- and tri-peptides containing proline. Multiple transcript variants encoding different isoforms have been found for this gene.
• Form: Liquid
• Molecular Mass: 54 kDa
• AA Sequence: AAATGPSFWLGNETLKVPLALFALNRQRLCERLRKNPAVQAGSIVVLQGG EETQRYCTDTGVLFRQESFFHWAFGVTEPGCYGVIDVDTGKSTLFVPRLP ASHATWMGKIHSKEHFKEKYAVDDVQYVDEIASVLTSQKPSVLLTLRGVN TDSGSVCREASFDGISKFEVNNTILHPEIVECRVFKTDMELEVLRYTNKI SSEAHREVMKAVKVGMKEYELESLFEHYCYSRGGMRHSSYTCICGSGENS AVLHYGHAGAPNDRTIQNGDMCLFDMGGEYYCFASDITCSFPANGKFTAD QKAVYEAVLRSSRAVMGAMKPGVWW PDMHRLADRIHLEELAHMGILSGSVDAMVQAHLGAVFMPHGLGHFLGIDV HDVGGYPEGVERIDEPGLRSLRTARHLQPGMVLTVEPGIYFIDHLLDEAL ADPARASFFNREVLQRFRGFGGVRIEEDVVVTDSGIELLTCVPRTVEEIE ACMAGCDKAFTPFSGPK
• Endotoxin: < 1.000 Eu/µg
• Purity: >95% by SDS-PAGE.>95% pure, as determined by SEC-HPLC and reducing SDS-PAGE. Supplied as an 0.2 µM filtered solution.
• Applications: SDS-PAGE; HPLC
• Storage: Shipped on Dry Ice. Store at -20°C or -80°C. Avoid freeze / thaw cycle.pH: 7.40Constituent: 100% PBS

Gene Information

• Gene Name: PEPD peptidase D [ Homo sapiens (human) ]
• Official Symbol: PEPD
• Synonyms: PEPD; PROLIDASE; peptidase D; xaa-Pro dipeptidase; imidodipeptidase; X-Pro dipeptidase; proline dipeptidase; aminoacyl-L-proline hydrolase; NP_000276.2; EC 3.4.13.9; NP_001159528.1; NP_001159529.1
• Gene ID: 5184
• mRNA Refseq: NM_000285
• Protein Refseq: NP_000276
• MIM: 613230
• UniProt ID: P12955
• Chromosome Location: 19q13.11
• Function: aminopeptidase activity; dipeptidase activity; manganese ion binding