Recombinant Human PDZ Binding Kinase, His-tagged

• Cat.No.: PBK-377H
• Product Overview: Recombinant humanPBK was expressed in Insect cells with a His tag. Its molecular weight is41000 Dalton.

Specification

• Species: Human
• Source: Insect Cells
• Tag: His
• Description: PBK is aserine/threonine kinase that is related to the dual specificmitogen-activated protein kinase kinase (MAPKK). The kinase is up-regulatedin a variety of hematological malignancies, participates in activatinglymphoid cells, and supports testicular function (spermatogenesis). Nospecial measures were taken to activate this kinase.
• Form: Liquid in 50 mMTris, pH 7.5 + 150 mM NaCl + 0.5 mM EDTA + 0.02% Triton X-100 + 2 mM DTT +50% glycerol.
• Molecular Weight: 41.0 kDa
• Storage: Stable for 6 monthsin working aliquots at -80°C. Avoid repeated freeze-thaw cycles.
• OfficialSymbol: PBK

Gene Information

• Gene Name: PBK PDZ binding kinase [ Homo sapiens ]
• Synonyms: PBK; PDZ bindingkinase; SPK; CT84; TOPK; Nori-3; FLJ14385; PDZ-binding kinase; cancer/testisantigen 84; Cancer/testis antigen 84; MAPKK-like protein kinase;serine/threonine protein kinase; T-LAK cell-originated protein kinase;Spermatogenesis-related protein kinase; EC 2.7.12.2; Lymphokine-activatedkiller T-cell-originated protein kinase
• Gene ID: 55872
• mRNA Refseq: NM_018492
• Protein Refseq: NP_060962
• MIM: 611210
• UniProt ID: Q96KB5
• Chromosome Location: 8p21.2
• Function: ATP binding;nucleotide binding; protein binding; protein serine/threonine kinase activity