Recombinant Human PBK Protein, MYC/DDK-tagged

• Cat.No.: PBK-427H
• Product Overview: Recombinant human PBK protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: This gene encodes a serine/threonine protein kinase related to the dual specific mitogen-activated protein kinase kinase (MAPKK) family. Evidence suggests that mitotic phosphorylation is required for its catalytic activity. The encoded protein may be involved in the activation of lymphoid cells and support testicular functions, with a suggested role in the process of spermatogenesis. Overexpression of this gene has been implicated in tumorigenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013].
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
• Molecular Mass: 35.9 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: PDZ binding kinase [ Homo sapiens ]
• Official Symbol: PBK
• Synonyms: CT84; HEL164; Nori-3; SPK; TOPK
• Gene ID: 55872
• mRNA Refseq: NM_018492.2
• Protein Refseq: NP_060962.2
• MIM: 611210
• UniProt ID: Q96KB5