Recombinant Human PDRG1, His-tagged

• Cat.No.: PDRG1-2858H
• Product Overview: Recombinant human PDRG1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. MW = 17.6 kDa (153aa) confirmed by MALDI-TOF.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: PDRG1, also known as PDRG or C20orf126, is a 133 amino acid protein that localizes to the cytoplasm and belongs to the prefoldin subunit β family. Expressed predominately in normal testicular tissue, PDRG1 is functionally induced by ultraviolet light and is thought to play a role in chaperone-mediated protein folding, possibly playing a role in cellular degradation. It is associated with Creutzfeldt-Jakob disease, amyotrophic lateral sclerosis, spinal muscular atrophy, ring chromosome 20 epilepsy syndrome and Alagille syndrome.
• Sequences Of Amino Acids: MGSSHHHHHH SSGLVPRGSH MLSPEAERVL RYLVEVEELA EEVLADKRQI VDLDTKRNQN REGLRALQKD LSLSEDVMVC FGNMFIKMPH PETKEMIEKD QDHLDKEIEK LRKQLKVKVN RLFEAQGKPE LKGFNLNPLN QDELKALKVI LKG
• Purity: > 90% by SDS – PAGE.
• Form: Liquid. In 20 mM Tris-HCl buffer (pH8.0) containing 0.2M NaCl, 5mM DTT, 20% glycerol.
• Concentration: 0.5 mg/ml (determined by Bradford assay).
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: PDRG1 p53 and DNA-damage regulated 1 [ Homo sapiens ]
• Synonyms: PDRG1; p53 and DNA-damage regulated 1; PDRG; C20orf126; p53 and DNA damage-regulated protein 1; chromosome 20 open reading frame 126; dJ310O13.3
• Gene ID: 81572
• mRNA Refseq: NM_030815
• Protein Refseq: NP_110442
• MIM: 610789
• UniProt ID: Q9NUG6
• Chromosome Location: 20q11.21
• Function: unfolded protein binding