Recombinant Human PDLIM7 cell lysate

• Cat.No.: PDLIM7-1326HCL

Specification

• Species: Human
• Tag: Non
• Description: The protein encoded by this gene is representative of a family of proteins composed of conserved PDZ and LIM domains. LIM domains are proposed to function in protein-protein recognition in a variety of contexts including gene transcription and development and in cytoskeletal interaction. The LIM domains of this protein bind to protein kinases, whereas the PDZ domain binds to actin filaments. The gene product is involved in the assembly of an actin filament-associated complex essential for transmission of ret/ptc2 mitogenic signaling. The biological function is likely to be that of an adapter, with the PDZ domain localizing the LIM-binding proteins to actin filaments of both skeletal muscle and nonmuscle tissues. Alternative splicing of this gene results in multiple transcript variants.
• Size: 100 ul
• Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
• Applications: Western Blot

Gene Information

• Gene Name: PDLIM7 PDZ and LIM domain 7 (enigma) [ Homo sapiens ]
• Official Symbol: PDLIM7
• Synonyms: PDLIM7; PDZ and LIM domain 7 (enigma); PDZ and LIM domain protein 7; ENIGMA; LMP; 1110003B01Rik; protein enigma; LIM domain protein; Lim mineralization protein 3; LMP1; LMP3
• Gene ID: 9260
• mRNA Refseq: NM_005451
• Protein Refseq: NP_005442
• MIM: 605903
• UniProt ID: Q9NR12
• Chromosome Location: 5q35.3
• Pathway: Signaling events regulated by Ret tyrosine kinase, organism-specific biosystem
• Function: metal ion binding; protein binding; zinc ion binding