Recombinant Human PDK4 Protein, MYC/DDK-tagged

• Cat.No.: PDK4-823H
• Product Overview: Recombinant human PDK4 protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: This gene is a member of the PDK/BCKDK protein kinase family and encodes a mitochondrial protein with a histidine kinase domain. This protein is located in the matrix of the mitrochondria and inhibits the pyruvate dehydrogenase complex by phosphorylating one of its subunits, thereby contributing to the regulation of glucose metabolism. Expression of this gene is regulated by glucocorticoids, retinoic acid and insulin. [provided by RefSeq, Jul 2008].
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
• Molecular Mass: 46.3 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: pyruvate dehydrogenase kinase 4[ Homo sapiens ]
• Official Symbol: PDK4
• Synonyms: FLJ40832
• Gene ID: 5166
• mRNA Refseq: NM_002612.3
• Protein Refseq: NP_002603
• UniProt ID: Q16654