Recombinant Human PDIA2 Protein, Myc/DDK-tagged, C13 and N15-labeled

Cat.No. : PDIA2-2676H
Product Overview : PDIA2 MS Standard C13 and N15-labeled recombinant protein (NP_006840) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
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Species : Human
Source : HEK293
Tag : DDK&Myc
Description : This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, two catalytically active thioredoxin (TRX) domains, two TRX-like domains and a C-terminal ER-retention sequence. The protein plays a role in the folding of nascent proteins in the endoplasmic reticulum by forming disulfide bonds through its thiol isomerase, oxidase, and reductase activity. The encoded protein also possesses estradiol-binding activity and can modulate intracellular estradiol levels.
Molecular Mass : 58 kDa
AA Sequence : MSRQLLPVLLLLLLRASCPWGQEQGARSPSEEPPEEEIPKEDGILVLSRHTLGLALREHPALLVEFYAPWCGHCQALAPEYSKAAAVLAAESMVVTLAKVDGPAQRELAEEFGVTEYPTLKFFRNGNRTHPEEYTGPRDAEGIAEWLRRRVGPSAMRLEDEAAAQALIGGRDLVVIGFFQDLQDEDVATFLALAQDALDMTFGLTDRPRLFQQFGLTKDTVVLFKKFDEGRADFPVDEELGLDLGDLSRFLVTHSMRLVTEFNSQTSAKIFAARILNHLLLFVNQTLAAHRELLAGFGEAAPRFRGQVLFVVVDVAADNEHVLQYFGLKAEAAPTLRLVNLETTKKYAPVDGGPVTAASITAFCHAVLNGQVKPYLLSQEIPPDWDQRPVKTLVGKNFEQVAFDETKNVFVKFYAPWCTHCKEMAPAWEALAEKYQDHEDIIIAELDATANELDAFAVHGFPTLKYFPAGPGRKVIEYKSTRDLETFSKFLDNGGVLPTEEPPEEPAAPFPEPPANSTMGSKEELTRTRPLEQKLISEEDLAANDILDYKDDDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
Gene Name PDIA2 protein disulfide isomerase family A member 2 [ Homo sapiens (human) ]
Official Symbol PDIA2
Synonyms PDIA2; protein disulfide isomerase family A, member 2; PDIP, protein disulfide isomerase, pancreatic, protein disulfide isomerase associated 2; protein disulfide-isomerase A2; PDA2; PDI; PDIR; protein disulfide isomerase A2; Rho GDP dissociation inhibitor gamma; pancreatic protein disulfide isomerase; protein disulfide isomerase, pancreatic; protein disulfide isomerase-associated 2; pancreas-specific protein disulfide isomerase; PDIP;
Gene ID 64714
mRNA Refseq NM_006849
Protein Refseq NP_006840
MIM 608012
UniProt ID Q13087

Not For Human Consumption!

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