Recombinant Human PDE5A, GST-tagged

• Cat.No.: PDE5A-1603H
• Product Overview: Recombinant Human PDE5A protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: GST
• Protein Length: 320-481aa
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: PDE5A phosphodiesterase 5A, cGMP-specific [ Homo sapiens ]
• Official Symbol: PDE5A
• Synonyms: PDE5A; phosphodiesterase 5A, cGMP-specific; cGMP-specific 3,5-cyclic phosphodiesterase; phosphodiesterase isozyme 5; cGMP-specific phosphodiesterase PDE5A2; cGMP-specific phosphodiesterase type 5A; cGMP-binding cGMP-specific 3,5-cyclic nucleotide phosphodiesterase; CN5A; PDE5; CGB-PDE
• Gene ID: 8654
• mRNA Refseq: NM_001083
• Protein Refseq: NP_001074
• MIM: 603310
• UniProt ID: O76074
• Chromosome Location: 4q27
• Pathway: Hemostasis, organism-specific biosystem; Nitric oxide stimulates guanylate cyclase, organism-specific biosystem; Platelet homeostasis, organism-specific biosystem; Purine metabolism, organism-specific biosystem; Purine metabolism, conserved biosystem; cGMP effects, organism-specific biosystem
• Function: 3,5-cyclic-GMP phosphodiesterase activity; 3,5-cyclic-nucleotide phosphodiesterase activity; cGMP binding; hydrolase activity; metal ion binding; nucleotide binding; zinc ion binding