Recombinant Human PDE2A Protein, His-tagged

• Cat.No.: PDE4B-146H
• Product Overview: Recombinant human C-terminal His-tagged PDE2A protein (215-900) was expressed in insect cells.

Specification

• Description: Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. Plays an important role in growth and invasion of malignant melanoma cells.
• Source: Insect cell
• Species: Human
• Tag: His
• Form: Lyophilized
• Molecular Mass: 80 kDa
• Protein length: 215-900
• Endotoxin: <1.0 EU/μg, determined by the LAL endotoxin assay
• Purity: ≥90% estimated by SDS-PAGE
• Stability: ≥ 9 months
• Storage: At -80 centigrade.
• Storage Buffer: Lyophilized from sterile 20mM Tris, pH 7.4, with 500 mM sodium chloride and 10% glycol

Gene Information

• Gene Name: PDE2A phosphodiesterase 2A [ Homo sapiens (human) ]
• Official Symbol: PDE2A
• Synonyms: PDE2A; phosphodiesterase 2A; PDE2A1; PED2A4; cGSPDE; CGS-PDE; IDDPADS; cGMP-dependent 3',5'-cyclic phosphodiesterase; cGMP-stimulated phosphodiesterase 1; cGMP-stimulated phosphodiesterase 2; cGMP-stimulated phosphodiesterase 4; cyclic GMP-stimulated phosphodiesterase; phosphodiesterase 2A, cGMP-stimulated; EC 3.1.4.17
• Gene ID: 5138
• mRNA Refseq: NM_002599
• Protein Refseq: NP_002590
• MIM: 602658
• UniProt ID: O00408