Recombinant Human PDE12 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: PDE12-4245H
• Product Overview: PDE12 MS Standard C13 and N15-labeled recombinant protein (NP_808881) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: PDE12 (Phosphodiesterase 12) is a Protein Coding gene. Diseases associated with PDE12 include Noonan Syndrome 2 and Microphthalmia With Limb Anomalies. Gene Ontology (GO) annotations related to this gene include poly(A)-specific ribonuclease activity. An important paralog of this gene is CNOT6.
• Source: HEK293
• Species: Human
• Tag: Myc&DDK
• Molecular Mass: 67.2 kDa
• AA Sequence: MWRLPGARAALRVIRTAVEKLSRAEAGSQTAAGAMERAVVRCVPSEPKLSLSFALADGSHKNMQRDQSEPLGRVLSRIATNALKGHAKAAAAKKSRKSRPNASGGAACSGPGPEPAVFCEPVVKLYYREEAVAEDVLNVDAWQDGAVLQIGDVKYKVERNPPAFTELQLPRYIMAGFPVCPKLSLEFGDPASSLFRWYKEAKPGAAEPEVGVPSSLSPSSPSSSWTETDVEERVYTPSNADIGLRLKLHCTPGDGQRFGHSRELESVCVVEAGPGTCTFDHRHLYTKKVTEDALIRTVSYNILADTYAQTEFSRTVLYPYCAPYALELDYRQNLIQKELTGYNADVICLQEVDRAVFSDSLVPALEAFGLEGVFRIKQHEGLATFYRKSKFSLLSQHDISFYEALESDPLHKELLEKLVLYPSAQEKVLQRSSVLQVSVLQSTKDSSKRICVANTHLYWHPKGGYIRLIQMAVALAHIRHVSCDLYPGIPVIFCGDFNSTPSTGMYHFVINGSIPEDHEDWASNGEEERCNMSLTHFFKLKSACGEPAYTNYVGGFHGCLDYIFIDLNALEVEQVIPLPSHEEVTTHQALPSVSHPSDHIALVCDLKWKTRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: PDE12 phosphodiesterase 12 [ Homo sapiens (human) ]
• Official Symbol: PDE12
• Synonyms: PDE12; phosphodiesterase 12; 2,5-phosphodiesterase 12; 2 PDE; 2 phosphodiesterase; DKFZp667B1218; 2-PDE; 2-phosphodiesterase
• Gene ID: 201626
• mRNA Refseq: NM_177966
• Protein Refseq: NP_808881
• MIM: 616519
• UniProt ID: Q6L8Q7