Recombinant Human PCSK4 cell lysate

• Cat.No.: PCSK4-1317HCL

Specification

• Species: Human
• Tag: Non
• Description: Proprotein convertases, including PCSK4, are calcium-dependent serine proteases related to bacterial subtilisins and to yeast kexin. These enzymes process precursor proteins to their active forms by selective cleavage of the polypeptide at sites following paired basic amino acids. In mammals, this family comprises PC1 (MIM 162150), PC2 (MIM 162151), PC4, PC5 (MIM 600488), furin (FUR; MIM 136950), and PACE4 (MIM 167405). Substrates for these enzymes range from prohormones to precursors for growth factors to cell surface receptors and viral surface glycoproteins (Cao et al., 2001 [PubMed 11776387]).
• Size: 100 ul
• Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
• Applications: Western Blot

Gene Information

• Gene Name: PCSK4 proprotein convertase subtilisin/kexin type 4 [ Homo sapiens ]
• Official Symbol: PCSK4
• Synonyms: PCSK4; proprotein convertase subtilisin/kexin type 4; DKFZp434B217; MGC34749; PC4; SPC5
• Gene ID: 54760
• mRNA Refseq: NM_017573
• Protein Refseq: NP_060043
• MIM: 600487
• UniProt ID: Q6UW60
• Chromosome Location: 19p13.3
• Function: peptidase activity; serine-type endopeptidase activity