Recombinant Human PCNA Protein, MYC/DDK-tagged

• Cat.No.: PCNA-626H
• Product Overview: Recombinant human PCNA protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome. [provided by RefSeq, Jul 2008].
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
• Molecular Mass: 28.6 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: proliferating cell nuclear antigen[ Homo sapiens ]
• Official Symbol: PCNA
• Synonyms: ATLD2
• Gene ID: 5111
• mRNA Refseq: NM_002592.2
• Protein Refseq: NP_002583.1
• MIM: 176740
• UniProt ID: P12004