Recombinant Human PCDHGB5 Protein, MYC/DDK-tagged
Cat.No. : | PCDHGB5-540H |
Product Overview : | Recombinant human PCDHGB5 protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293. |
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Species : | Human |
Source : | HEK293 |
Tag : | Myc&DDK |
Description : | This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes. [provided by RefSeq, Jul 2008]. |
Form : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol. |
Molecular Mass : | 86 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Concentration : | >50 ug/mL as determined by microplate BCA method |
Gene Name | protocadherin gamma subfamily B, 5[ Homo sapiens ] |
Official Symbol | PCDHGB5 |
Synonyms | PCDH-GAMMA-B5; PCDH-GAMMA-B5 |
Gene ID | 56101 |
mRNA Refseq | NM_018925.2 |
Protein Refseq | NP_061748.1 |
MIM | 606302 |
UniProt ID | Q9Y5G0 |
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Not For Human Consumption!
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