Recombinant Human PCDHGB5 Protein, MYC/DDK-tagged

Cat.No. : PCDHGB5-540H
Product Overview : Recombinant human PCDHGB5 protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293.
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Species : Human
Source : HEK293
Tag : Myc&DDK
Description : This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes. [provided by RefSeq, Jul 2008].
Form : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
Molecular Mass : 86 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name protocadherin gamma subfamily B, 5[ Homo sapiens ]
Official Symbol PCDHGB5
Synonyms PCDH-GAMMA-B5; PCDH-GAMMA-B5
Gene ID 56101
mRNA Refseq NM_018925.2
Protein Refseq NP_061748.1
MIM 606302
UniProt ID Q9Y5G0

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