Recombinant Human PCDHB8 Protein, His-tagged

• Cat.No.: PCDHB8-1920H
• Product Overview: Recombinant Human PCDHB8 Protein (Ser61-Ser220) with N-His tag was expressed in E. coli.

Specification

• Description: This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 21.9 kDa
  Accurate Molecular Mass: 23 kDa
• Protein length: Ser61-Ser220
• Purity: > 90%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in PBS or others.

Gene Information

• Gene Name: PCDHB8 protocadherin beta 8 [ Homo sapiens (human) ]
• Official Symbol: PCDHB8
• Synonyms: PCDHB8; protocadherin beta 8; PCDH3I; PCDH-BETA8; protocadherin beta-8; protocadherin-3i
• Gene ID: 56128
• mRNA Refseq: NM_019120
• Protein Refseq: NP_061993
• MIM: 606334
• UniProt ID: Q9UN66