Recombinant Human PCBP4 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: PCBP4-5772H
• Product Overview: PCBP4 MS Standard C13 and N15-labeled recombinant protein (NP_127501) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a member of the KH-domain protein subfamily. Proteins of this subfamily, also referred to as alpha-CPs, bind to RNA with a specificity for C-rich pyrimidine regions. Alpha-CPs play important roles in post-transcriptional activities and have different cellular distributions. This gene is induced by the p53 tumor suppressor, and the encoded protein can suppress cell proliferation by inducing apoptosis and cell cycle arrest in G(2)-M. This gene's protein is found in the cytoplasm, yet it lacks the nuclear localization signals found in other subfamily members. Multiple alternatively spliced transcript variants have been described, but the full-length nature for only some has been determined.
• Source: HEK293
• Species: Human
• Tag: Myc&DDK
• Molecular Mass: 41.5 kDa
• AA Sequence: MSGSDGGLEEEPELSITLTLRMLMHGKEVGSIIGKKGETVKRIREQSSARITISEGSCPERITTITGSTAAVFHAVSMIAFKLDEDLCAAPANGGNVSRPPVTLRLVIPASQCGSLIGKAGTKIKEIRETTGAQVQVAGDLLPNSTERAVTVSGVPDAIILCVRQICAVILESPPKGATIPYHPSLSLGTVLLSANQGFSVQGQYGAVTPAEVTKLQQLSSHAVPFATPSVVPGLDPGTQTSSQEFLVPNDLIGCVIGRQGSKISEIRQMSGAHIKIGNQAEGAGERHVTITGSPVSIALAQYLITACLETAKSTSGGTPSSAPADLPAPFSPPLTALPTAPPGLLGTPYAISLSNFIGLKPMPFLALPPASPGPPPGLAAYTAKMAAANGSKKAERQKFSPYTRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: PCBP4 poly(rC) binding protein 4 [ Homo sapiens (human) ]
• Official Symbol: PCBP4
• Synonyms: PCBP4; poly(rC) binding protein 4; poly(rC)-binding protein 4; alphaCP 4 protein; LIP4; LYST interacting protein; MCG10; RNA binding protein MCG10; alpha-CP4; LYST-interacting protein; CBP
• Gene ID: 57060
• mRNA Refseq: NM_033008
• Protein Refseq: NP_127501
• MIM: 608503
• UniProt ID: P57723