Recombinant Human PANX1 protein, His & T7-tagged

• Cat.No.: PANX1-1348H
• Product Overview: Recombinant Human PANX1 aa. (Cys228~Asn411 (Accession # Q96RD7) fused with N-terminal His & T7 tag was produced in E. coli cells.

Specification

• Description: The protein encoded by this gene belongs to the innexin family. Innexin family members are the structural components of gap junctions. This protein and pannexin 2 are abundantly expressed in central nerve system (CNS) and are coexpressed in various neuronal populations. Studies in Xenopus oocytes suggest that this protein alone and in combination with pannexin 2 may form cell type-specific gap junctions with distinct properties.
• Source: E. coli
• Species: Human
• Tag: His&T7
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 24.5kDa
• Protein length: Cys228~Asn411
• Endotoxin: <1.0EU per 1µg (determined by the LAL method)
• Purity: >95%
• Characteristic: The isoelectric point is 5.7.
• Applications: SDS-PAGE; WB; ELISA; IP.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage buffer: Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl.
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.

Gene Information

• Gene Name: PANX1 pannexin 1 [ Homo sapiens (human) ]
• Official Symbol: PANX1
• Synonyms: PANX1; pannexin 1; PX1; MRS1; UNQ2529; pannexin-1; innexin
• Gene ID: 24145
• mRNA Refseq: NM_015368.3
• Protein Refseq: NP_056183.2
• UniProt ID: Q96RD7