Recombinant Human PAK6 Protein (G383-Y674), His tagged

• Cat.No.: PAK6-1109H
• Product Overview: Recombinant Human 6His-TEV-PAK6(G383-Y674) Protein was expressed in E. coli.

Specification

• Description: Serine/threonine protein kinase that plays a role in the regulation of gene transcription. The kinase activity is induced by various effectors including AR or MAP2K6/MAPKK6. Phosphorylates the DNA-binding domain of androgen receptor/AR and thereby inhibits AR-mediated transcription. Inhibits also ESR1-mediated transcription. May play a role in cytoskeleton regulation by interacting with IQGAP1. May protect cells from apoptosis through phosphorylation of BAD.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Liquid
• Protein length: G383-Y674
• Endotoxin: < 0.01 EU per μg of the protein
• Purity: 90%
• Stability: Samples are stable for up to twelve months from date of receipt at -20 to -80 centigrade.
• Storage: Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Storage Buffer: Supplied as sterile 50 mM Tris-HCl (pH7.5), 200 mM NaCl, 20% glycerol
• Shipping: It is shipped out with blue ice.

Gene Information

• Gene Name: PAK6 p21 protein (Cdc42/Rac)-activated kinase 6 [ Homo sapiens (human) ]
• Official Symbol: PAK6
• Synonyms: PAK6; p21 protein (Cdc42/Rac)-activated kinase 6; p21(CDKN1A) activated kinase 6; serine/threonine-protein kinase PAK 6; PAK5; PAK-5; PAK-6; p21-activated kinase 6; p21(CDKN1A)-activated kinase 6; p21-activated protein kinase 6
• Gene ID: 56924
• mRNA Refseq: NM_001128628
• Protein Refseq: NP_001122100
• MIM: 608110
• UniProt ID: Q9NQU5