Recombinant Human PA2G4 Protein (Ser2-Asp394), His tagged

• Cat.No.: PA2G4-4783H
• Product Overview: Recombinant human PA2G4 (Ser2-Asp394) fused with His tag was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: Ser2-Asp394
• Description: EBP1, also known as PA2G4, is an RNA-binding protein which belongs to the peptidase M24 family. It can be detected n several cell lines tested, including primary and transformed cell lines. EBP1 also present in pre-ribosomal ribonucleoprotein complexes and may be involved in ribosome assembly and the regulation of intermediate and late steps of rRNA processing. This protein is a transcriptional co-repressor of androgen receptor-regulated genes and other cell cycle regulatory genes through its interactions with histone deacetylases. PA2G4 can interact with the cytoplasmic domain of the ErbB3 receptor and may contribute to transducing growth regulatory signals. EBP1 has been implicated in growth inhibition and the induction of differentiation of human cancer cells. It seems to be involved in growth regulation. EBP1 also mediates cap-independent translation of specific viral IRESs (internal ribosomal entry site) .
• Form: Lyophilized powder/frozen liquid
• Molecular Mass: 43.86 kDa
• Purity: >90% as determined by SDS-PAGE.
• Notes: For research use only.
• Storage: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt.
• Storage Buffer: Supplied as solution form in PBS, pH 7.5 or lyophilized from PBS, pH 7.5.
• Reconstitution: Reconstitute in sterile water for a stock solution.
• Shipping: They are shipped out with dry ice/blue ice unless customers require otherwise.

Gene Information

• Gene Name: PA2G4 proliferation-associated 2G4, 38kDa [ Homo sapiens (human) ]
• Official Symbol: PA2G4
• Synonyms: PA2G4; proliferation-associated 2G4, 38kDa; proliferation associated 2G4, 38kD; proliferation-associated protein 2G4; erbB3-binding protein 1; ErbB-3 binding protein 1; ErbB3-binding protein Ebp1; cell cycle protein p38-2G4 homolog; EBP1; HG4-1; p38-2G4
• Gene ID: 5036
• mRNA Refseq: NM_006191
• Protein Refseq: NP_006182
• MIM: 602145
• UniProt ID: Q9UQ80