Recombinant Human OXSM protein, His-tagged

• Cat.No.: OXSM-2347H
• Product Overview: Recombinant Human OXSM(28-459aa) fused with His tag at N-terminal was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 28-459 a.a.
• Description: OXSM is a beta-ketoacyl synthetase. The enzyme is required for elongation of fatty acid chains in the mitochondria. Alternatively spliced transcript variants have been described.
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT
• Molecular Mass: 48.1 kDa (455aa) confirmed by MALDI-TOF
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSKRKFFGT VPISRLHRRV VITGIGLVTP LGVGTHLVWD RLIGGESGIV SLVGEEYKSI PCSVAAYVPRGSDEGQFNEQ NFVSKSDIKS MSSPTIMAIG AAELAMKDSG WHPQSEADQV ATGVAIGMGM IPLEVVSETA LNFQTKGYNK VSPFFVPKILVNMAAGQVSI RYKLKGPNHA VSTACTTGAH AVGDSFRFIA HGDADVMVAG GTDSCISPLS LAGFSRARAL STNSDPKLAC RPFHPKRDGFVMGEGAAVLV LEEYEHAVQR RARIYAEVLG YGLSGDAGHI TAPDPEGEGA LRCMAAALKD AGVQPEEISY INAHATSTPL GDAAENKAIKHLFKDHAYAL AVSSTKGATG HLLGAAGAVE AAFTTLACYY QKLPPTLNLD CSEPEFDLNY VPLKAQEWKT EKRFIGLTNS FGFGGTNATLCIAGL
• Purity: > 90% by SDS - PAGE
• Storage: Can be stored at +4 centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20 centigrade or -70 centigrade. Avoid repeated freezing and thawing cycles.
• Concentration: 0.5 mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: OXSM 3-oxoacyl-ACP synthase, mitochondrial [ Homo sapiens ]
• Official Symbol: OXSM
• Synonyms: KS; KASI; FASN2D
• Gene ID: 54995
• mRNA Refseq: NM_017897.2
• Protein Refseq: NP_060367
• MIM: 610324
• UniProt ID: Q9NWU1
• Chromosome Location: 3p24.2
• Pathway: Fatty acid biosynthesis, organism-specific biosystem;Fatty acid biosynthesis, conserved biosystem;Fatty acid biosynthesis, elongation, organism-specific biosystem;Fatty acid biosynthesis, elongation, conserved biosystem;fatty acid biosynthesis initiation II, organism-specific biosystem;palmitate biosynthesis I (animals), organism-specific biosystem
• Function: 3-oxoacyl-[acyl-carrier-protein] synthase activity