Recombinant Human oxidative stress responsive 1, His-tagged

• Cat.No.: OXSR1-625H
• Product Overview: OXSR1, 1-527aa, Human, His tag, E.coli

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 1-527 a.a.
• Description: OXSR1 is a member of the neuronal calcium sensor gene family, which encode calcium-binding proteins expressed predominantly in neurons. This protein regulates G protein-coupled receptor phosphorylation in a calcium-dependent manner and can substitute for calmodulin. It is associated with secretory granules and modulates synaptic transmission and synaptic plasticity. Multiple transcript variants encoding different isoforms have been found for this gene. Recombinant human OXSR1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
• Form: Liquid. In 1X Phosphate Buffered Saline (pH7.4) containing 30% glycerol, 1mM DTT
• Molecular Mass: 60.4. kDa (550aa)
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMSEDSSA LPWSINRDDY ELQEVIGSGA TAVVQAAYCA PKKEKVAIKR INLEKCQTSM DELLKEIQAM SQCHHPNIVS YYTSFVVKDE LWLVMKLLSG GSVLDIIKHI VAKGEHKSGV LDESTIATIL REVLEGLEYL HKNGQIHRDV KAGNILLGED GSVQIADFGV SAFLATGGDI TRNKVRKTFV GTPCWMAPEV MEQVRGYDFK ADIWSFGITA IELATGAAPY HKYPPMKVLM LTLQNDPPSL ETGVQDKEML KKYGKSFRKM ISLCLQKDPE KRPTAAELLR HKFFQKAKNK EFLQEKTLQR APTISERAKK VRRVPGSSGR LHKTEDGGWE WSDDEFDEES EEGKAAISQL RSPRVKESIS NSELFPTTDP VGTLLQVPEQ ISAHLPQPAG QIATQPTQVS LPPTAEPAKT AQALSSGSGS QETKIPISLV LRLRNSKKEL NDIRFEFTPG RDTAEGVSQE LISAGLVDGR DLVIVAANLQ KIVEEPQSNR SVTFKLASGV EGSDIPDDGK LIGFAQLSIS
• Purity: >85% by SDS - PAGE
• Storage: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
• Concentration: 0.5mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: OXSR1 oxidative-stress responsive 1 [ Homo sapiens ]
• Official Symbol: OXSR1
• Synonyms: OXSR1; oxidative-stress responsive 1; OSR1; serine/threonine-protein kinase OSR1; KIAA1101; oxidative stress-responsive 1 protein
• Gene ID: 9943
• mRNA Refseq: NM_005109
• Protein Refseq: NP_005100
• MIM: 604046
• UniProt ID: O95747
• Chromosome Location: 3p22.2
• Function: ATP binding; magnesium ion binding; nucleotide binding; protein serine/threonine kinase activity