Recombinant Human OSTN, His-tagged

• Cat.No.: OSTN-3502H
• Product Overview: Recombinant human OSTN protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: Osteocrin (OSTN), also known as Musclin, contains two conserved sequence motifs homologous to the natriuretic peptide family. This protein appears to modulate osteoblastic differentiation and highly expressed in cells of osteoblast lineage and in skeletal muscle tissue. It could also function as an autocrine and paracrine factor linked to glucose metabolism in skeletal muscle.
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 2mM DTT, 20% glycerol, 200mM NaCl
• Molecular Weight: 14.0kDa (127aa) confirmed by MALDI-TOF(Molecular weight on SDS-PAGE will appear higher)
• Purity: > 95% by SDS - PAGE
• Concentration: 0.5mg/ml (determined by BCA)
• Sequences of amino acids: MGSSHHHHHH SSGLVPRGSH MVDVTTTEAF DSGVIDVQST PTVREEKSAT DLTAKLLLLD ELVSLENDVI ETKKKRSFSG FGSPLDRLSA GSVDHKGKQR KVVDHPKRRF GIPMDRIGRN RLSNSRG
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: OSTN osteocrin [ Homo sapiens ]
• Synonyms: Osteocrin; MUSCLIN; OSTN; Musclin
• Gene ID: 344901
• mRNA Refseq: NM_198184
• Protein Refseq: NP_937827
• MIM: 610280
• UniProt ID: P61366
• Chromosome Location: 3q28
• Function: hormone activity