Recombinant Human OSBPL2 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: OSBPL2-4605H
• Product Overview: OSBPL2 MS Standard C13 and N15-labeled recombinant protein (NP_653081) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although the encoded protein contains only the sterol-binding domain. In vitro studies have shown that the encoded protein can bind strongly to phosphatic acid and weakly to phosphatidylinositol 3-phosphate, but cannot bind to 25-hydroxycholesterol. The protein associates with the Golgi apparatus. Transcript variants encoding different isoforms have been described.
• Source: HEK293
• Species: Human
• Tag: Myc&DDK
• Molecular Mass: 55.2 kDa
• AA Sequence: MNGEEEFFDAVTGFDSDNSSGEFSEANQKVTGMIDLDTSKNNRIGKTGERPSQENGIQKHRTSLPAPMFSRSDFSVWTILKKCVGLELSKITMPIAFNEPLSFLQRITEYMEHVYLIHRASCQPQPLERMQSVAAFAVSAVASQWERTGKPFNPLLGETYELIREDLGFRFISEQVSHHPPISAFHSEGLNHDFLFHGSIYPKLKFWGKSVEAEPRGTITLELLKHNEAYTWTNPTCCVHNVIIGKLWIEQYGTVEILNHRTGHKCVLHFKPCGLFGKELHKVEGHIQDKNKKKLFMIYGKWTECLWGIDPVSYESFKKQERRGDHLRKAKLDEDSGKADSDVADDVPVAQETVQVIPGSKLLWRINTRPPNSAQMYNFTSFTVSLNELETGMEKTLPPTDCRLRPDIRGMENGNMDLASQEKERLEEKQREARRERAKEEAEWQTRWFYPGNNPYTGTPDWLYAGDYFERNFSDCPDIYTRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: OSBPL2 oxysterol binding protein-like 2 [ Homo sapiens (human) ]
• Official Symbol: OSBPL2
• Synonyms: OSBPL2; oxysterol binding protein-like 2; oxysterol binding protein like 2; oxysterol-binding protein-related protein 2; KIAA0772; ORP 2; OSBP-related protein 2; oxysterol-binding protein-like 2; ORP2; ORP-2; MGC4307; MGC8342; FLJ20223
• Gene ID: 9885
• mRNA Refseq: NM_144498
• Protein Refseq: NP_653081
• MIM: 606731
• UniProt ID: Q9H1P3