Recombinant Human NUP62, T7-tagged

• Cat.No.: NUP62-2956H
• Product Overview: Recombinant Human NUP62 (1-522 aa) is expressed inE.Coliwith a T7 tag at N-terminus.

Specification

• Species: Human
• Source: E.coli
• Tag: T7
• Protein Length: 1-522 a.a.
• Description: The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. The protein encoded by this gene is a member of the FG-repeat containing nucleoporins and is localized to the nuclear pore central plug. This protein associates with the importin alpha/beta complex which is involved in the import of proteins containing nuclear localization signals. Multiple transcript variants of this gene encode a single protein isoform.
• MW: 53269 Da.
• Purity: 95%.
• Formulation: 10 mM Tris. pH 8.0. 0.1% Triton X-100.0.002% NaN3.
• Application: MS. SDS.

Gene Information

• Gene Name: NUP62 nucleoporin 62kDa [ Homo sapiens ]
• Synonyms: NUP62; nucleoporin 62kDa;DKFZp547L134, FLJ20822, FLJ43869, IBSN, MGC841, SNDI, p62; 62 kDa nucleoporin; nuclear pore glycoprotein p62; nucleoporin Nup62
• Gene ID: 23636
• mRNA Refseq: NM_001193357
• Protein Refseq: NP_001180286
• MIM: 605815
• UniProt ID: P37198
• Chromosome Location: 19q13.33
• Pathway: Metabolism of carbohydrates; Transmembrane transport of small molecules
• Function: PTB domain binding; SH2 domain binding; contributes_to nucleocytoplasmic transporter activity; protein serine/threonine kinase activity; receptor signaling complex scaffold activity