NUP62
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Official Full Name
nucleoporin 62 -
Overview
component of the nuclear pore complex; may be involved in nuclear pore transport -
Synonyms
NUP62;nucleoporin 62;nuclear pore glycoprotein p62;62 kDa nucleoporin;nucleoporin 62kD;nucleoporin 62kDa;Nup 62;p62;nucleoporin Nup62;nuclear pore glycoprotein 62;Np62
Recombinant Proteins
- Human
- Rhesus macaque
- Rat
- E.coli
- Mammalian Cells
- Sf9 Cells
- Wheat Germ
- HEK293
- Yeast
- Insect Cells
- T7
- His
- GST
- Myc&DDK
- Non
- His&Fc&Avi
- His&Myc
- Flag
Involved Pathway
NUP62 involved in several pathways and played different roles in them. We selected most pathways NUP62 participated on our site, such as RNA transport, which may be useful for your reference. Also, other proteins which involved in the same pathway with NUP62 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| RNA transport | PABPC1L2A,EIF5B,AAAS,EIF4A3,NUPL1,PABPC1B,STRAP,MAGOH,SUMO2,POP1 |
Protein Function
NUP62 has several biochemical functions, for example, PTB domain binding,SH2 domain binding,chromatin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NUP62 itself. We selected most functions NUP62 had, and list some proteins which have the same functions with NUP62. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| thyroid hormone receptor binding | ZNHIT3,GTF2B,TAF7,MED24,NCOA3,OASL,THRAP3,MED4,GAS2L1,NR0B2 |
| protein binding | TBX3,CPNE3,RANBP6,PLD3,INPP5D,AP4M1,MYL12B,USH1C,OLFM4,TPSAB1 |
| kinesin binding | GOLSYN,KLC3,ATCAY,CLSTN1,KLC2,AP1AR,MAPK8IP3,SERPINB1A,IFT88,SNCA |
| SH2 domain binding | LAX1,IRS1,CRK,LILRB1,SRC,LCK,ARHGAP5,PTK2,SKAP1,MS4A2 |
| receptor signaling complex scaffold activity | LRRK2,SPAG9,MMS19,SPAG9A,DEDD2,CD3G,G3BP2,GRIP2A,NCK1,SHANK1 |
| PTB domain binding | INSR,INPP5D,APP |
| ubiquitin binding | SMAD3,USP5,UBAP1,FAM125A,OTUB1,VPS36,USP13,CXCR4,OTUB1A,NEDD4 |
| structural constituent of nuclear pore | NUP54,NUP205,NDC1,NUP155,NUP107,NUP85,NUP98,NUP133,NUP62L,NUP62CL |
| chromatin binding | CUX1,SOX9,SNAI2,NUPR1,Ar,REL,TADA2A,GATA4,BRD4,ZFP143 |
Interacting Protein
NUP62 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NUP62 here. Most of them are supplied by our site. Hope this information will be useful for your research of NUP62.
NXF1;THAP1;NUP54;NUPL1
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References
- Chang, CW; Lee, CP; et al. BGLF4 Kinase Modulates the Structure and Transport Preference of the Nuclear Pore Complex To Facilitate Nuclear Import of Epstein-Barr Virus Lytic Proteins. JOURNAL OF VIROLOGY 89:1703-1718(2015).
- Senecal, JL; Isabelle, C; et al. An Autoimmune Myositis-Overlap Syndrome Associated With Autoantibodies to Nuclear Pore Complexes Description and Long-Term Follow-up of the Anti-Nup Syndrome. MEDICINE 93:361-372(2014).
