Recombinant Human NUDT3, His-tagged

• Cat.No.: NUDT3-27534TH
• Product Overview: Recombinant full length Human NUDT3 with an N terminal His tag ; predicted mwt: 21.6 kDa

Specification

• Species: Human
• Source: E.coli
• Tag: His
• ProteinLength: 172 amino acids
• Description: NUDT3 belongs to the MutT, or Nudix, protein family. Nudix proteins act as homeostatic checkpoints at important stages in nucleoside phosphate metabolic pathways, guarding against elevated levels of potentially dangerous intermediates, like 8-oxo-dGTP, which promotes AT-to-CG transversions (Safrany et al.
• Conjugation: HIS
• Molecular Weight: 21.600kDa inclusive of tags
• Form: Liquid
• Purity: >95% by SDS-PAGE
• Storage buffer: Preservative: NoneConstituents: 20% Glycerol, 5mM DTT, 200mM Sodium chloride, 20mM Tris HCl, pH 8
• Storage: Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Sequences of amino acids: MGSSHHHHHH SSGLVPRGSH MMKLKSNQTR TYDGDGYKKR AACLCFRSES EEEVLLVSSS RHPDRWIVPG GGMEPEEEPS VAAVREVCEEAGVKGTLGRL VGIFENQERK HRTYVYVLIV TEVLEDWEDS VNIGRKREWF KIEDAIKVLQ YHKPVQASYF ETLRQGYSAN NGTPVVATTYSVSAQSSMSG IR

Gene Information

• Gene Name: NUDT3 nudix (nucleoside diphosphate linked moiety X)-type motif 3 [ Homo sapiens ]
• Official Symbol: NUDT3
• Synonyms: NUDT3; nudix (nucleoside diphosphate linked moiety X)-type motif 3; diphosphoinositol polyphosphate phosphohydrolase 1; DIPP
• Gene ID: 11165
• mRNA Refseq: NM_006703
• Protein Refseq: NP_006694
• MIM: 609228
• Uniprot ID: O95989
• Chromosome Location: 6p21.2
• Function: diphosphoinositol-polyphosphate diphosphatase activity; hydrolase activity; magnesium ion binding