Recombinant Human NTN4 protein, His & GST-tagged

• Cat.No.: NTN4-1863H
• Product Overview: Recombinant Human NTN4 aa. (Glu349~His592 (Accession # Q9HB63)) fused with N-terminal His & GST tag was produced in E. coli cells.

Specification

• Species: Human
• Source: E.coli
• Tag: GST&His
• Protein Length: Glu349~His592
• Description: This gene encodes a member of the netrin family of proteins, which function in various biological processes including axon guidance, tumorogenesis, and angiogenesis. Netrins are laminin-related proteins that have an N-terminal laminin-type domain, epidermal growth factor-like repeat domain, and a positively charged heparin-binding domain at the C-terminus. The protein encoded by this gene is involved in processes including neurite growth and migration, angiogenesis and mural cell adhesion to endothelial cells. Alternative splicing results in multiple transcript variants.
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 59.3kDa.
• Endotoxin: <1.0EU per 1ug (determined by the LAL method)
• Purity: >95%
• Characteristic: The isoelectric point is 7.
• Applications: SDS-PAGE; WB; ELISA; IP.
• Stability: The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. (Referring from China Biological Products Standard, which was calculated by the Arrhenius equation.) The loss of this protein is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage Buffer: Supplied as lyophilized form in 20mM Tris, 500mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% sarcosyl, 5% trehalose, and preservative.
• Reconstitution: Reconstitute in ddH2O.

Gene Information

• Gene Name: NTN4 netrin 4 [ Homo sapiens (human) ]
• Official Symbol: NTN4
• Synonyms: Cyp1a1; cytochrome P450, family 1, subfamily a, polypeptide 1; AHH; AHRR; CP11; CYPIA1; P450-1; cytochrome P450 1A1; cytochrome P450 subfamily I, polypeptide 1; cytochrome P450, 1a1, aromatic compound inducible; cytochrome P450-P1
• Gene ID: 59277
• mRNA Refseq: NM_001329700.1
• Protein Refseq: NP_001316629.1
• UniProt ID: Q9HB63