Recombinant Human NR2C1 protein, His & T7-tagged

• Cat.No.: NR2C1-1087H
• Product Overview: Recombinant Human NR2C1 aa. (Met1~Phe324 (Accession # P13056) fused with N-terminal His & T7 tag was produced in E. coli cells.

Specification

• Species: Human
• Source: E.coli
• Tag: His&T7
• Protein Length: Met1~Phe324
• Description: This gene encodes a nuclear hormone receptor characterized by a highly conserved DNA binding domain (DBD), a variable hinge region, and a carboxy-terminal ligand binding domain (LBD) that is typical for all members of the steroid/thyroid hormone receptor superfamily. This protein also belongs to a large family of ligand-inducible transcription factors that regulate gene expression by binding to specific DNA sequences within promoters of target genes. Multiple alternatively spliced transcript variants have been described, but the full-length nature of some of these variants has not been determined.
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 39.3kDa.
• Endotoxin: <1.0EU per 1µg (determined by the LAL method)
• Purity: >90%
• Characteristic: The isoelectric point is 6.5.
• Applications: SDS-PAGE; WB; ELISA; IP.
• Stability: The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. (Referring from China Biological Products Standard, which was calculated by the Arrhenius equation.) The loss of this protein is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage buffer: Supplied as lyophilized form in 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% sarcosyl, 5% trehalose, and preservative.
• Reconstitution: Reconstitute in sterile ddH2O.

Gene Information

• Gene Name: NR2C1 nuclear receptor subfamily 2 group C member 1 [ Homo sapiens (human) ]
• Official Symbol: NR2C1
• Synonyms: NR2C1; nuclear receptor subfamily 2 group C member 1; TR2; nuclear receptor subfamily 2 group C member 1; TR2 nuclear hormone receptor; nuclear receptor subfamily 2, group C isoform; orphan nuclear receptor TR2
• Gene ID: 7181
• mRNA Refseq: NM_001032287.2
• Protein Refseq: NP_001027458.1
• UniProt ID: P13056