NR2C1
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Official Full Name
NR2C1 nuclear receptor subfamily 2, group C, member 1 -
Synonyms
NR2C1;nuclear receptor subfamily 2, group C, member 1;TR2;nuclear receptor subfamily 2 group C member 1;TR2 11;orphan nuclear receptor TR2;TR2 nuclear hormone receptor;nuclear receptor subfamily 2, group C isoform
Recombinant Proteins
- Mouse
- Human
- Zebrafish
- Chicken
- Cynomolgus
- Mammalian Cells
- E.coli
- HEK293
- Wheat Germ
- In Vitro Cell Free System
- His
- T7
- Non
- Avi
- Fc
- GST
Involved Pathway
NR2C1 involved in several pathways and played different roles in them. We selected most pathways NR2C1 participated on our site, such as Gene Expression,Generic Transcription Pathway,Nuclear Receptor transcription pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with NR2C1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Regulation of Androgen receptor activity | SENP1,TRIM24,SRY,SPDEF,SMARCA2,HOXB13,KAT7,NR2C2,NR0B1,GATA2 |
| Nuclear Receptor transcription pathway | NR2C2,NR6A1A,ESRRGA,NR6A1,RORAA,NR2F6,NR0B1,NR2E3,NR2C2AP,ESRRG |
| Gene Expression | ALKBH8,ZNF225,MED10,AGO3B,ZNF597,ARHGEF38,ZNF3,ZFP90,ZNF649,BRF2 |
| Signaling events mediated by HDAC Class I | SIRT5,MXD1,GATA2,GATA1,SIRT2,SIRT7,TFCP2,WDR77,SIRT4,FKBP3 |
| Generic Transcription Pathway | ZFP30,ZNF285A,ZNF490,ZNF668,ZNF718,ZNF573,ZNF606,ZNF75A,RRAGB,ZNF707 |
Protein Function
NR2C1 has several biochemical functions, for example, DNA binding,RNA polymerase II core promoter proximal region sequence-specific DNA binding,histone deacetylase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NR2C1 itself. We selected most functions NR2C1 had, and list some proteins which have the same functions with NR2C1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| receptor activity | KLRK1,RAMP3,GRIA2B,CADM2,ITGB3A,TNFRSF10A,GRIN1A,ANTXR2B,TNPO3,VMN1R49 |
| steroid hormone receptor activity | NR1H5,RARB,PAQR7A,PPARAB,ESRRGB,NR1D4A,NR6A1B,NR2F1A,ESRRGA,NR2C2 |
| protein homodimerization activity | GLIPR2,CCDC88A,MYOM1,ANXA9,EFR3A,AXIN1,XCL1,GLA,XPA,DMRT1 |
| DNA binding | RUNX2B,AHRRB,NKX6.2,ZNF688,RFXANK,DDX3Y,TET2,SP9,ZNF692,HOXC9A |
| histone deacetylase binding | RELA,PRDM1,HES1,SP2,CEBPA,RBBP4,NKX3-1,SUDS3,MAGEA2B,DDX20 |
| protein binding | DDAH2,HEMGN,PTGDR,HIST1H3H,TOE1,AGFG1,IL5RA,SNCA,RPN1,PCGF1 |
| zinc ion binding | ERI2,PRKCBA,KLF4,RNF213,MT1X,ZNF259,CECR1,USP3,RBM4.1,ZCCHC7 |
| transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding | NKX6-1,ZBTB7A,IFI16,NFIL3,NR2E1,ZGPAT,ZFPM2,YY1,CC2D1A,TBX3 |
| RNA polymerase II core promoter proximal region sequence-specific DNA binding | ZKSCAN3,KLF16,ZNF502,JUNBB,MSX2,ZNF92,ISL1,NACC2,CC2D1B,ZIC1 |
Interacting Protein
NR2C1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NR2C1 here. Most of them are supplied by our site. Hope this information will be useful for your research of NR2C1.
ESR1;q81jh7_bacan;NUDT3
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