Recombinant Human NOTCH2(Leu26-Gln530) Protein, C-6*His-tagged

• Cat.No.: NOTCH2-720H
• Product Overview: Recombinant Human NOTCH2(Q04721)(Leu26-Gln530) Protein, fused with a 6*His tag at the C-terminus, was produced in HEK293.

Specification

• Source: HEK293
• Species: Human
• Tag: His
• Form: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
• Molecular Mass: The recombinant Human NOTCH2 Protein has a predicted molecular mass of 54.9kDa, it migrates with an apparent molecular mass of 60-70kDa under reducing conditions.
• AA Sequence: Leu26-Gln530
• Endotoxin: < 0.01 EU per μg of the protein as determined by the LAL method.
• Purity: Greater than 95% as determined by reducing SDS-PAGE.
• Storage: Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.25 mg/ml. Centrifuge the vial at 4°C before opening to recover the entire contents.
• Shipping: In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.
  Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
• Protein length: 26-530 a.a.
• Publications:
  The Special Role of JAK/STAT, and Notch Signaling Pathways in Cancer Pathogenesis (2023)
  The Special Role of JAK/STAT, and Notch Signaling Pathways in Cancer Pathogenesis (2023)

Gene Information

• Gene Name: NOTCH2 notch 2 [ Homo sapiens ]
• Official Symbol: NOTCH2
• Synonyms: NOTCH2; notch 2; Notch (Drosophila) homolog 2 , Notch homolog 2 (Drosophila); neurogenic locus notch homolog protein 2; Notch homolog 2; hN2; AGS2; HJCYS
• Gene ID: 4853
• mRNA Refseq: NM_001200001
• Protein Refseq: NP_001186930
• MIM: 600275
• UniProt ID: Q04721