Recombinant Human NOSTRIN Protein, GST-tagged

• Cat.No.: NOSTRIN-5995H
• Product Overview: Human NOSTRIN full-length ORF ( NP_001034813.1, 1 a.a. - 506 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Species: Human
• Source: Wheat Germ
• Tag: GST
• Description: Nitric oxide (NO) is a potent mediator in biologic processes such as neurotransmission, inflammatory response, and vascular homeostasis. NOSTRIN binds the enzyme responsible for NO production, endothelial NO synthase (ENOS; MIM 163729), and triggers the translocation of ENOS from the plasma membrane to vesicle-like subcellular structures, thereby attenuating ENOS-dependent NO production.[supplied by OMIM
• Molecular Mass: 84.1 kDa
• AA Sequence: MRDPLTDCPYNKVYKNLKEFSQNGENFCKQVTSVLQQRANLEISYAKGLQKLASKLSKALQNTRKSCVSSAWAWASEGMKSTADLHQKLGKAIELEAIKPTYQVLNVQEKKRKSLDNEVEKTANLVISNWNQQIKAKKKLMVSTKKHEALFQLVESSKQSMTEKEKRKLLNKLTKSTEKLEKEDENYYQKNMAGYSTRLKWENTLENCYQSILELEKERIQLLCNNLNQYSQHISLFGQTLTTCHTQIHCAISKIDIEKDIQAVMEETAILSTENKSEFLLTDYFEEDPNSAMDKERRKSLLKPKLLRLQRDIEKASKDKEGLERMLKTYSSTSSFSDAKSQKDTAALMDENNLKLDLLEANSYKLSSMLAELEQRPQPSHPCSNSIFRWREKEHTHSYVKISRPFLMKRLENIVSKASSGGQSNPGSSTPAPGAAQLSSRLCKALYSFQARQDDELNLEKGDIVIIHEKKEEGWWFGSLNGKKGHFPAAYVEELPSNAGNTATKA
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: NOSTRIN nitric oxide synthase trafficker [ Homo sapiens ]
• Official Symbol: NOSTRIN
• Synonyms: NOSTRIN; nitric oxide synthase trafficker; nostrin; MGC20702; BM247 homolog; ENOS traffic inducer; eNOS-trafficking inducer; nitric oxide synthase trafficking; nitric oxide synthase traffic inducer; endothelial nitric oxide synthase traffic inducer; ortholog of mouse disabled 2 interacting proein 2; DaIP2
• Gene ID: 115677
• mRNA Refseq: NM_001039724
• Protein Refseq: NP_001034813
• MIM: 607496
• UniProt ID: Q8IVI9