Recombinant Human NOS1AP Protein, His-tagged

• Cat.No.: NOS1AP-471H
• Product Overview: Recombinant Human NOS1AP(Thr285~Val506) fused with His tag at N-terminal was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: Thr285~Val506
• Description: This gene encodes a cytosolic protein that binds to the signaling molecule, neuronal nitric oxide synthase (nNOS). This protein has a C-terminal PDZ-binding domain that mediates interactions with nNOS and an N-terminal phosphotyrosine binding (PTB) domain that binds to the small monomeric G protein, Dexras1. Studies of the related mouse and rat proteins have shown that this protein functions as an adapter protein linking nNOS to specific targets, such as Dexras1 and the synapsins. Alternative splicing results in multiple transcript variants encoding different isoforms.
• Form: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Molecular Mass: 28.3kDa
• Identity: Reconstitute in PBS or others
• Endotoxin: <1.0EU per 1µg (determined by the LAL method)
• Purity: > 95%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
  If bio-activity of the protein is needed, please check active protein
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Reconstitution: Reconstitute in PBS or others

Gene Information

• Gene Name: NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein [ Homo sapiens ]
• Official Symbol: NOS1AP
• Synonyms: NOS1AP; nitric oxide synthase 1 (neuronal) adaptor protein; carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein; C terminal PDZ domain ligand of neuronal nitric oxide synthase; CAPON; KIAA0464; nitric oxide synthase 1 adaptor protein; C-terminal PDZ ligand of neuronal nitric oxide synthase protein; C-terminal PDZ domain ligand of neuronal nitric oxide synthase (CAPON); ligand of neuronal nitric oxide synthase with carboxyl-terminal PDZ domain; 6330408P19Rik; MGC138500
• Gene ID: 9722
• mRNA Refseq: NM_001126060
• Protein Refseq: NP_001119532
• MIM: 605551
• UniProt ID: O75052