Recombinant Human NMU protein, His & GST-tagged

• Cat.No.: NMU-5751H
• Product Overview: Recombinant Human NMU aa. (Ala35~Ile158 (Accession # P48645)) fused with N-terminal His & GST tag was produced in E. coli cells.

Specification

• Species: Human
• Source: E.coli
• Tag: His&GST
• ProteinLength: Ala35~Ile158
• Description: This gene encodes a member of the neuromedin family of neuropeptides. The encoded protein is a precursor that is proteolytically processed to generate a biologically active neuropeptide that plays a role in pain, stress, immune-mediated inflammatory diseases and feeding regulation. Increased expression of this gene was observed in renal, pancreatic and lung cancers. Alternative splicing results in multiple transcript variants encoding different isoforms. Some of these isoforms may undergo similar processing to generate the mature peptide.
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 44.5kDa
• Endotoxin: <1.0EU per 1µg (determined by the LAL method)
• Purity: >95%
• Characteristic: The isoelectric point is 9.8.
• Applications: SDS-PAGE; WB; ELISA; IP.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage buffer: Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl.
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.

Gene Information

• Gene Name: NMU neuromedin U [ Homo sapiens (human) ]
• Official Symbol: NMU
• Synonyms: NMU; neuromedin U; neuromedin-U; prepro-NMU
• Gene ID: 10874
• mRNA Refseq: NM_001292045.1
• Protein Refseq: NP_001278974.1
• UniProt ID: P48645