Recombinant Human NLRP8 Protein, MYC/DDK-tagged

• Cat.No.: NLRP8-1007H
• Product Overview: Recombinant human NLRP8 protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293.

Specification

• Description: This gene encodes a member of the nucleotide-binding oligomerization domain/ leucine rich repeat/ pyrin domain containing (NLRP) subfamily, which belongs to the Nod-like receptor family of proteins. NLRP genes play roles in the mammalian innate immune system through inflammasome formation and activation of caspases. In addition, NLRP genes have been found to function during mammalian reproduction. Consistent with a function during human preimplantation development, this gene is expressed at high levels in oocytes with decreased levels in embryos. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016].
• Source: HEK293
• Species: Human
• Tag: Myc&DDK
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
• Molecular Mass: 119.2 kDa
• Purity: >50 ug/mL as determined by microplate BCA method
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: NLRP8 NLR family, pyrin domain containing 8 [ Homo sapiens ]
• Official Symbol: NLRP8
• Synonyms: CLR19.2; NALP8; NOD16; PAN4
• Gene ID: 126205
• mRNA Refseq: NM_176811
• Protein Refseq: NP_789781
• MIM: 609659
• UniProt ID: Q86W28