Recombinant Human NLGN4Y, His-tagged

• Cat.No.: NLGN4Y-5228H
• Product Overview: Recombinant Human NLGN4Y (44-675) Protein, C-His Tag (rhNLGN4Y) Gln 44 - Ser676 (Accession # NM_014893.4 ) was produced in human HEK293 cells

Specification

• Species: Human
• Source: HEK293
• Tag: His
• Protein Length: 44-676 a.a.
• Description: Neuroligin 4, Y-linked (NLGN4Y) a type I membrane protein that belongs to the family of neuroligins, which are cell adhesion molecules present at the postsynaptic side of the synapse, and may be essential for the formation of functional synapses. Alternatively spliced transcript variants have been found for NLGN4Y gene. NLGN4Y was expressed in fetal and adult brain, prostate, testis, pancreas. NLGN4Y is homologous with its X-linked homolog, NLGN4X.
• Predicted N Terminal: Gln 44
• Form: Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally Mannitol or Trehalose are added as protectants before lyophilization.
• Molecular Mass: 72.23 kDa. Protein migrates as 70-95 kDa in reduced SDS-PAGE resulting from different extent glycosylation.
• Endotoxin: Less than 1.0 EU per μg of the rhNLGN4Y by the LAL method.
• Purity: >95% as determined by SDS-PAGE. All lots are greater than 95% pure.
• Storage: Avoid repeated freeze-thaw cycles.No activity loss was observed after storage at:In lyophilized state for 1 year (4oC-8oC); After reconstitution under sterile conditions for 1 month (4oC-8oC) or 3 months (-20oC to -70oC).

Gene Information

• Gene Name: NLGN4Y neuroligin 4, Y-linked [ Homo sapiens ]
• Official Symbol: NLGN4Y
• Synonyms: NLGN4Y; neuroligin 4, Y-linked; neuroligin 4, Y linked; neuroligin-4, Y-linked; KIAA0951
• Gene ID: 22829
• mRNA Refseq: NM_001164238
• Protein Refseq: NP_001157710
• MIM: 400028
• UniProt ID: Q8NFZ3
• Chromosome Location: Y
• Function: NOT carboxylesterase activity; neurexin family protein binding; protein binding; receptor activity