Recombinant Human NFKBIE protein, His-tagged

• Cat.No.: NFKBIE-232H
• Product Overview: Recombinant Human NFKBIE fused with His tag at N-terminal was expressed in Insect cells.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: The protein encoded by this gene binds to components of NF-kappa-B, trapping the complex in the cytoplasm and preventing it from activating genes in the nucleus. Phosphorylation of the encoded protein targets it for destruction by the ubiquitin pathway, which activates NF-kappa-B by making it available to translocate to the nucleus.
• Form: 25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1 % Sarkosyl.
• Molecular Mass: 29.3 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon [ Homo sapiens ]
• Official Symbol: NFKBIE
• Synonyms: NFKBIE; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon; NF-kappa-B inhibitor epsilon; IKBE; ikB-E; ikB-epsilon; NF-kappa-BIE; ikappaBepsilon; I-kappa-B-epsilon
• Gene ID: 4794
• mRNA Refseq: NM_004556
• Protein Refseq: NP_004547
• MIM: 604548
• UniProt ID: O00221