Recombinant Human NEBL Protein, His&GST-tagged

• Cat.No.: NEBL-1820H
• Product Overview: Recombinant Human NEBL Protein (Met1-Ala264) with N-His&GST tag was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: GST&His
• Protein Length: Met1-Ala264
• Description: This gene encodes a nebulin like protein that is abundantly expressed in cardiac muscle. The encoded protein binds actin and interacts with thin filaments and Z-line associated proteins in striated muscle. This protein may be involved in cardiac myofibril assembly. A shorter isoform of this protein termed LIM nebulette is expressed in non-muscle cells and may function as a component of focal adhesion complexes. Alternate splicing results in multiple transcript variants.
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 60.3 kDa
  Accurate Molecular Mass: 56 kDa
• Purity: > 90%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in PBS or others.

Gene Information

• Gene Name: NEBL nebulette [ Homo sapiens (human) ]
• Official Symbol: NEBL
• Synonyms: NEBL; nebulette; LIM-nebulette; actin-binding Z-disk protein; LASP2; LNEBL; FLJ53769; MGC119746; MGC119747
• Gene ID: 10529
• mRNA Refseq: NM_001173484
• Protein Refseq: NP_001166955
• MIM: 605491
• UniProt ID: O76041