NEBL

  • Official Full Name

    nebulette

  • Overview

    This gene encodes a nebulin like protein that is abundantly expressed in cardiac muscle. The encoded protein binds actin and interacts with thin filaments and Z-line associated proteins in striated muscle. This protein may be involved in cardiac myofibril assembly. A shorter isoform of this protein termed LIM nebulette is expressed in non-muscle cells and may function as a component of focal adhesion complexes. Alternate splicing results in multiple transcript variants.

  • Synonyms

    NEBL;nebulette;LIM-nebulette;actin-binding Z-disk protein;LASP2;LNEBL;FLJ53769;MGC119746;MGC119747

Recombinant Proteins

  • Human
  • Mouse
  • Zebrafish
  • Chicken
  • E.coli
  • Mammalian Cells
  • HEK293
  • GST
  • His
  • DDK
  • Myc
  • Avi
  • Fc
Cat.# Product name Source (Host) Species Tag Protein Length Price
NEBL-1246H Recombinant Human NEBL, GST-tagged E.coli Human GST 201-550aa
NEBL-10552M Recombinant Mouse NEBL Protein Mammalian Cells Mouse His
NEBL-2224Z Recombinant Zebrafish NEBL Mammalian Cells Zebrafish His
NEBL-6058C Recombinant Chicken NEBL Mammalian Cells Chicken His
NEBL-1485H Recombinant Human NEBL Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293 Human DDK&Myc
NEBL-1820H Recombinant Human NEBL Protein, His&GST-tagged E.coli Human GST&His Met1-Ala264
Nebl-4351M Recombinant Mouse Nebl Protein, Myc/DDK-tagged HEK293 Mouse DDK&Myc
NEBL-590H Recombinant Human NEBL Protein, MYC/DDK-tagged HEK293 Human DDK&Myc
NEBL-5997M Recombinant Mouse NEBL Protein, His (Fc)-Avi-tagged HEK293 Mouse Avi&Fc&His
NEBL-5997M-B Recombinant Mouse NEBL Protein Pre-coupled Magnetic Beads HEK293 Mouse

    Involved Pathway

    NEBL involved in several pathways and played different roles in them. We selected most pathways NEBL participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with NEBL were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    Protein Function

    NEBL has several biochemical functions, for example, actin filament binding,cytoskeletal protein binding,filamin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NEBL itself. We selected most functions NEBL had, and list some proteins which have the same functions with NEBL. You can find most of the proteins on our site.

    Function Related Protein
    protein binding IFITM1,Raet1c,ORC4L,A1CF,SIX5,SIVA1,TPSB2,EPAS1,PTGES2,VGLL2
    structural constituent of muscle MYBPC2,MYBPH,SMTN,SYNM,MYL6B,SORBS2,ACTN3,MYH11,TPM2,DAG1
    filamin binding PDLIM2,MICALL2,FBLIM1,FAM101B,ZNF664-FAM101A,TMEM67,HSPB7,FAM101A
    tropomyosin binding S100A6,LMOD3,LMOD1,TMOD4,TMOD1,TNNT2A,TNNT1,TMOD2,TMOD3,LMOD2A
    actin filament binding TULP1,LIMA1,TRIOBP,CORO2A,VIL1,MICALL2,WIPF2,EZR,GAS7,PLS1
    cytoskeletal protein binding PTPN4,NCKIPSD,CAPN2,MSNA,PDLIM3,PACSIN1,PACSIN2,FRMD3,PACSIN1A,EZRB

    Interacting Protein

    NEBL has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NEBL here. Most of them are supplied by our site. Hope this information will be useful for your research of NEBL.

    b2r8y4_human;HOMER3;TRIM27;GOLGA2;TRAF2;TRAF1;FLJ13057

    Resources

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