Recombinant Human NDUFB9 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: NDUFB9-6366H
• Product Overview: NDUFB9 MS Standard C13 and N15-labeled recombinant protein (NP_004996) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: The protein encoded by this gene is a subunit of the mitochondrial oxidative phosphorylation complex I (nicotinamide adenine dinucleotide: ubiquinone oxidoreductase). Complex I is localized to the inner mitochondrial membrane and functions to dehydrogenate nicotinamide adenine dinucleotide and to shuttle electrons to coenzyme Q. Complex I deficiency is the most common defect found in oxidative phosphorylation disorders and results in a range of conditions, including lethal neonatal disease, hypertrophic cardiomyopathy, liver disease, and adult-onset neurodegenerative disorders. Pseudogenes of this gene are found on chromosomes five, seven and eight. Alternative splicing results in multiple transcript variants.
• Molecular Mass: 21.8 kDa
• AA Sequence: MAFLASGPYLTHQQKVLRLYKRALRHLESWCVQRDKYRYFACLMRARFEEHKNEKDMAKATQLLKEAEEEFWYRQHPQPYIFPDSPGGTSYERYDCYKVPEWCLDDWHPSEKAMYPDYFAKREQWKKLRRESWEREVKQLQEETPPGGPLTEALPPARKEGDLPPLWWYIVTRPRERPMTRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: NDUFB9 NADH:ubiquinone oxidoreductase subunit B9 [ Homo sapiens (human) ]
• Official Symbol: NDUFB9
• Synonyms: NDUFB9; NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9, 22kDa; NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9 (22kD, B22); NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9; B22; complex I B22 subunit; LYRM3; UQOR22; CI-B22; complex I-B22; LYR motif-containing protein 3; NADH-ubiquinone oxidoreductase B22 subunit; FLJ22885; DKFZp566O173
• Gene ID: 4715
• mRNA Refseq: NM_005005
• Protein Refseq: NP_004996
• MIM: 601445
• UniProt ID: Q9Y6M9