Recombinant Human NBN Protein, His-tagged

Description :	Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation.
Source :	E. coli
Species :	Human
Tag :	His
Molecular Mass :	34 kDa
Protein length :	461-754
Purity :	> 80% as determined by SDS-PAGE and Coomassie blue staining
Stability :	Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage :	Store at -80 centigrade
Concentration :	> 50 µg/mL as determined by microplate BCA method
Storage Buffer :	25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol,1% Sarkosyl

Gene Name	NBN nibrin [ Homo sapiens (human) ]
Official Symbol	NBN
Synonyms	NBN; nibrin; ATV; NBS; P95; NBS1; AT-V1; AT-V2; nibrin; Nijmegen breakage syndrome 1 (nibrin); cell cycle regulatory protein p95; p95 protein of the MRE11/RAD50 complex
Gene ID	4683
mRNA Refseq	NM_001024688
Protein Refseq	NP_001019859
MIM	602667
UniProt ID	O60934