Recombinant Human NANOG

• Cat.No.: NANOG-28442TH
• Product Overview: Recombinant full length protein, corresponding to amino acids 2-305 of Human Nanog (34.5 kDa).

Specification

• Species: Human
• Source: E.coli
• Tag: Non
• Description: NANOG (pron. nanOg) is a transcription factor critically involved with self-renewal of undifferentiated embryonic stem cells. In humans, this protein is encoded by the NANOG gene.
• Tissue specificity: Expressed in testicular carcinoma and derived germ cell tumors (at protein level). Expressed in fetal gonads, ovary and testis. Also expressed in ovary teratocarcinoma cell line and testicular embryonic carcinoma. Not expressed in many somatic organs and
• Form: Lyophilised:Reconstitute to 1mg/ml using sterile water.
• Purity: >95% by SDS-PAGE
• Storage buffer: Preservative: NoneEndotoxin level is less than 0.1 ng per μg (1EU/μg).
• Storage: The lyophilized protein is stable for a few weeks at room temperature, but best stored at -20°C.
• Sequences of amino acids: SVDPACPQSL PCFEASDCKE SSPMPVICGP EENYPSLQMS SAEMPHTETV SPLPSSMDLL IQDSPDSSTS PKGKQPTSAE NSVAKKEDKV PVKKQKTRTV FSSTQLCVLN DRFQRQKYLS LQQMQELSNI LNLSYKQVKT WFQNQRMKSK RWQKNNWPKN SNGVTQKASA PTYPSLYSSY HQGCLVNPTG NLPMWSNQTW NNSTWSNQTQ NIQSWSNHSW NTQTWCTQSW NNQAWNSPFY NCGEESLQSC MQFQPNSPAS DLEAALEAAG EGLNVIQQTT RYFSTPQTMD LFLNYSMNMQ PEDV
• Sequence Similarities: Belongs to the Nanog homeobox family.Contains 1 homeobox DNA-binding domain.

Gene Information

• Gene Name: NANOG Nanog homeobox [ Homo sapiens ]
• Official Symbol: NANOG
• Synonyms: NANOG; Nanog homeobox; homeobox protein NANOG; FLJ12581; FLJ40451
• Gene ID: 79923
• mRNA Refseq: NM_024865
• Protein Refseq: NP_079141
• MIM: 607937
• Uniprot ID: Q9H9S0
• Chromosome Location: 12p13.31
• Pathway: Wnt Signaling Pathway and Pluripotency, organism-specific biosystem
• Function: DNA binding; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity