Recombinant Human NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase), His-tagged

Cat.No. : NDUFS6-252H
Product Overview : NDUFS6, 28-124aa, Human, His tag, E.coli
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Species : Human
Source : E.coli
Tag : His
Protein Length : 28-124 a.a.
Description : NDUFS6 is a subunit of the NADH:ubiquinone oxidoreductase (complex I), which is the first enzyme complex in the electron transport chain of mitochondria. This complex functions in the transfer of electrons from NADH to the respiratory chain. The subunit is one of seven subunits in the iron-sulfur protein fraction. Mutations cause mitochondrial complex I deficiency, a disease that causes a wide variety of clinical disorders, including neonatal disease and adult-onset neurodegenerative disorders. Recombinant human NDUFS6 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques
Form : Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 30% glycerol, 1mM DTT
Molecular Mass : 13.2kDa (120aa), confirmed by MALDI-TOF
AA Sequence : MGSSHHHHHH SSGLVPRGSH MGSFGVRVSP TGEKVTHTGQ VYDDKDYRRI RFVGRQKEVN ENFAIDLIAE QPVSEVETRV IACDGGGGAL GHPKVYINLD KETKTGTCGY CGLQFRQHHH
Purity : >90% by SDS - PAGE
Storage : Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Concentration : 0.25 mg/ml (determined by Bradford assay)
Gene Name NDUFS6 NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase) [ Homo sapiens ]
Official Symbol NDUFS6
Synonyms NDUFS6; NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase); NADH dehydrogenase (ubiquinone) Fe S protein 6 (13kD) (NADH coenzyme Q reductase); NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial; CI 13kA; complex I 13kDa subunit A; NADH dehydrogenase [ubiquinone] iron sulfur protein 6; mitochondrial; NADH:ubiquinone oxidoreductase NDUFS6 subunit; NADH-ubiquinone oxidoreductase 13 kDa-A subunit; complex I, mitochondrial respiratory chain, 13-kD subunit; CI-13kA; CI13KDA; CI-13kD-A;
Gene ID 4726
mRNA Refseq NM_004553
Protein Refseq NP_004544
MIM 603848
UniProt ID O75380
Chromosome Location 5p15.33
Pathway Alzheimers disease, organism-specific biosystem; Alzheimers disease, conserved biosystem; Electron Transport Chain, organism-specific biosystem; Huntingtons disease, organism-specific biosystem; Huntingtons disease, conserved biosystem; Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem;
Function NADH dehydrogenase (ubiquinone) activity; electron carrier activity;

Not For Human Consumption!

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