Recombinant Human Myotrophin, His-tagged

• Cat.No.: MTPN-2731H
• Product Overview: Recombinant human MTPN, fused to His-tag at N-terminus, was expressed inE.coliand purified by using conventional chromatography. MW =15.0 kDa(138aa), confirmed by MALDI-TOF.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: MTPN (myotrophin), an ankyrin repeat protein, is stimulates protein synthesis and cardiomyocyte growth to initiate cardiac hypertrophy by activating the NF-kappaB signaling cascade. This protein plays a potential role in cerebellar morphogenesis and may function in differentiation of cerebellar neurons, particularly of granule cells. Elevated levels of MTPN are expressed inhumandilated cardiomyopathic and ischemic hearts.
• Sequences Of Amino Acids: MGSSHHHHHH SSGLVPRGSH MCDKEFMWAL KNGDLDEVKD YVAKGEDVNR TLEGGRKPLH YAADCGQLEI LEFLLLKGAD INAPDKHHIT PLLSAVYEGH VSCVKLLLSK GADKTVKGPDGLTAFEATDN QAIKALLQ
• Form: Liquid. In 20 mM Tris-HCl Buffer (pH 8.0) containing 10% Glycerol.
• Purity: > 90% by SDS – PAGE.
• Concentration: 1 mg/ml (determined by Bradford assay).
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: MTPN myotrophin [ Homo sapiens ]
• Synonyms: MTPN; myotrophin; V-1; GCDP; FLJ31098; FLJ99857; protein V-1; granule cell differentiation protein; MYOTROPHIN
• Gene ID: 136319
• mRNA Refseq: NM_145808
• Protein Refseq: NP_665807
• MIM: 606484
• UniProt ID: P58546
• Chromosome Location: 7q33
• Function: protein binding