Recombinant Human MYOC

• Cat.No.: MYOC-29758TH
• Product Overview: Recombinant fragment: QLRKANDQSG RCQYTFSVAS PNESSCPEQS QAMSVIHNLQ RDSSTQRLDL EATKARLSSL ESLLHQLTLD QAARPQETQE GLQRELGTLR RERDQLETQT of Human Myocilin with N terminal proprietary tag, 36.63 kDa.

Specification

• Description: MYOC encodes the protein myocilin, which is believed to have a role in cytoskeletal function. MYOC is expressed in many occular tissues, including the trabecular meshwork, and was revealed to be the trabecular meshwork glucocorticoid-inducible response protein (TIGR). The trabecular meshwork is a specialized eye tissue essential in regulating intraocular pressure, and mutations in MYOC have been identified as the cause of hereditary juvenile-onset open-angle glaucoma.
• Protein length: 100 amino acids
• Molecular Weight: 36.630kDa inclusive of tags
• Source: Wheat germ
• Tissue specificity: Expressed in large amounts in various types of muscle, ciliary body, papillary sphincter, skeletal muscle, heart and other tissues. Expressed predominantly in the retina. In normal eyes, found in the inner uveal meshwork region and the anterior portion of
• Form: Liquid
• Purity: Proprietary Purification
• Storage buffer: pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequences of amino acids: QLRKANDQSGRCQYTFSVASPNESSCPEQSQAMSVIHNLQRDSSTQRLDLEATKARLSSLESLLHQLTLDQAARPQETQEGLQRELGTLRRERDQLETQT
• Sequence Similarities: Contains 1 olfactomedin-like domain.
• Tag: Non

Gene Information

• Gene Name: MYOC myocilin, trabecular meshwork inducible glucocorticoid response [ Homo sapiens ]
• Official Symbol: MYOC
• Synonyms: MYOC; myocilin, trabecular meshwork inducible glucocorticoid response; GLC1A; myocilin; JOAG1; TIGR
• Gene ID: 4653
• mRNA Refseq: NM_000261
• Protein Refseq: NP_000252
• MIM: 601652
• Uniprot ID: Q99972
• Chromosome Location: 1q23-q24
• Function: structural molecule activity